What is a major effect of cyanide on the body?

Cyanide is a potent inhibitor of cellular respiration, specifically targeting the mitochondrial electron transport chain. It binds to cytochrome c oxidase (complex IV), a key enzyme that plays a critical role in the electron transport process. By inhibiting this enzyme, cyanide effectively prevents cells from utilizing oxygen for aerobic respiration, which is essential for the production of ATP, the energy currency of the cell. As a result, even though oxygen is present in the bloodstream, the cells cannot use it, leading to a state of cellular hypoxia. This is why the major effect of cyanide on the body is that it prevents cells from using oxygen, causing a range of severe metabolic disturbances and, if not treated promptly, can lead to death.